Available PET Radioligands for Human Use

List of available PET radioligands injected into humans

 

Target

 

Radiotracer

 

Benzodiazepine antagonist

 

[11C]Flumazenil

 

Cannabinoid receptor type 1

 

[11C]JHU75528

 

Cerebral blood flow

 

[15O]water

 

Dopamine D2/D3 receptor

 

[11C]PHNO

 

Dopamine D2/D3 receptor

 

[11C]Raclopride

 

Dopamine transporter

 

[11C]PE2I

 

Extrastriatal dopamine D2

 

[11C]FLB457

 

Fibrillar amyloid-beta (Aβ) plaques

 

[11C]PIB

 

Fibrillar amyloid-beta (Aβ) plaques

 

[18F]BPIB

 

Glucose metabolism

 

[18F]FDG

 

Glycine transporter 1

 

[18F]CFpyPB

 

Histamine-3

 

[11C]GSK189254

 

Hypoxia

 

[18F]FMISO

 

Kappa antagonist

 

[11C]LY2795050

 

Kappa opioid

 

[11C]GR103545

 

Metabotropic glutamate receptor 5

 

[11C]ABP688

 

Metabotropic glutamate receptor 5

 

[18F]FPEB

 

Myocardial blood flow

 

82Rb

 

Nicotinic a4b2 receptors

 

[18F]NCFHEB

 

Norepinephrine transporter

 

[11C]MRB

 

Peripheral benzodiazepine receptor

 

[11C]PBR28

 

Phosphodiesterase-2A

 

[18F]PF-05270430

 

Serotonin 5HT1B receptor

 

[11C]P943

 

Serotonin 5-HT1A receptor antagonist

 

[11C]CUMI

 

Serotonin 5-HT2A receptor

 

[11C]MDL100907

 

Serotonin 5HT4 receptor

 

[11C]SB-207145

 

Serotonin 5-HT6 receptor

 

[11C]GSK-215083

 

Serotonin Transporter

 

[11C]AFM

 

Serotonin Transporter

 

[11C]DASB

 

Vesicular monoamine transporter 2

 

[18F](+)FP-DTBZ

 

Tracking protein synthesis

 

[11C]Methionine

Gallery of selected PET Radioligands

YSM placeholder

Cannabinoid receptor type 1

Radiotracer: [11C]JHU75528

Target: Cannabinoid receptor type 1

phno_cropped_avg

Dopamine D2/D3 receptor

Radiotracer: [11C]PHNO

Target: Dopamine D2/D3 receptor

YSM placeholder

Histamine-3

Radiotracer: [11C]GSK189254

Target: Histamine-3

fpeb_cropped

Metabotropic glutamate receptor 5

Radiotracer: [18F]FPEB

Target: Metabotropic glutamate receptor 5

abp_cropped

Metabotropic Glutamate Receptor 5

Radiotracer: [11C]ABP688

Target: Metabotropic glutamate receptor 5

YSM placeholder

Norepinephrine transporter

Radiotracer: [11C]MRB

Target: Norepinephrine transporter

mkap_cropped

Kappa opioid agonist

Radiotracer: [11C]GR103545

Target: Kappa opioid agonist

pkab_cropped

Kappa Opioid Antagonist

Radiotracer: [11C]LY2795050

Target: Kappa Opioid Antagonist

pbr28_cropped

Peripheral benzodiazepine receptor

Radiotracer:[11C]PBR28

Target: Peripheral benzodiazepine receptor

pta_cropped

Phosphodiesterase-2A

Radiotracer:[11F]PF-05270430

YSM placeholder

Serotonin 5HT1B Receptor

Radiotracer:[11C]P943

Target: Serotonin 5HT1B receptor

surf_cropped

Serotonin 5HT4 receptor

Radiotracer:[11C]SB-207145

Target: Serotonin 5HT4 receptor

quics_cropped

Serotonin 5-HT6 receptor antagonist

Radiotracer:[11C]GSK-215083

Target: Serotonin 5HT6 receptor

YSM placeholder

Serotonin transporter

Radiotracer: [11C]AFM

Target: Serotonin transporter

fpdtbz_cropped

VMAT2 / Beta cells

Radiotracer: [18F](+)FP-DTBZ

Target: VMAT2 / Beta cells